Influence of lack of blinding on the estimation of medication-related harms: a retrospective cohort study of randomized controlled trials.

Chang XuFengying ZhangSuhail A R DoiLuis Furuya-KanamoriLifeng LinHaitao ChuXi YangSheyu LiLiliane ZorzelaSu GolderYoon LokeSunita Vohra

Published in: BMC medicine (2024)

Lack of blinding of participants and health care providers in randomized controlled trials may underestimate medication-related harms. Adequate blinding in randomized trials, when feasible, may help safeguard against potential bias in estimating the effects of harms.

Keyphrases

healthcare
randomized controlled trial
clinical trial
emergency department
risk assessment
social media
drug induced
health information