Acute Respiratory Failure in Autoimmune Rheumatic Diseases: A Review.
Sofia PoliFrancesca SciorioGiorgio PiacentiniAngelo PietrobelliLuca PecoraroSara PieropanPublished in: Journal of clinical medicine (2024)
This review examines respiratory complications in autoimmune rheumatic diseases within intensive care units (ICUs). The respiratory system, primarily affected in diseases like rheumatoid arthritis, systemic lupus erythematosus, and scleroderma, often leads to respiratory failure. Common manifestations include alveolar hemorrhage, interstitial fibrosis, and acute respiratory distress syndrome. Early recognition and treatment of non-malignant conditions are crucial to prevent rapid disease progression, with ICU mortality rates ranging from 30% to 60%. Delayed immunosuppressive or antimicrobial therapy may result in organ system failure. Collaboration with rheumatic specialists is vital for accurate diagnosis and immediate intervention. Mortality rates for rheumatic diseases in the ICU surpass those of other conditions, underscoring the need for specialized care and proactive management. The review emphasizes comprehensive assessments, distinguishing disease-related complications from underlying issues, and the importance of vigilant monitoring to enhance patient outcomes.
Keyphrases
- respiratory failure
- mechanical ventilation
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- intensive care unit
- rheumatoid arthritis
- systemic lupus erythematosus
- risk factors
- disease activity
- palliative care
- cardiovascular events
- multiple sclerosis
- randomized controlled trial
- healthcare
- interstitial lung disease
- drug induced
- systemic sclerosis
- staphylococcus aureus
- high resolution
- quality improvement
- ankylosing spondylitis
- coronary artery disease
- hepatitis b virus
- mesenchymal stem cells
- cardiovascular disease
- type diabetes
- bone marrow
- mass spectrometry
- pain management
- smoking cessation
- affordable care act