The minimal important difference in obsessive-compulsive disorder: An analysis of double-blind SSRI trials in adults.
Sem E CohenJasper Brian ZantvoordTaina K MattilaBram W C StorosumAnthonius de BoerDamiaan A J P DenysPublished in: European psychiatry : the journal of the Association of European Psychiatrists (2024)
By linking the YBOCS to the CGI-I, this is the first study to propose an MID in OCD trials. Having a clearly defined MID can guide future clinical research and help interpretation of efficacy of existing interventions. Our results are clinician-based; however, there is further need for patient-reported outcomes as anchor to the YBOCS.