Holmium Complex with Phospholipids as 1 H NMR Relaxational Sensor of Temperature and Viscosity.

Published in: Molecules (Basel, Switzerland) (2022)

The sensitivity of Ho-phospholipid complexes to changes in the membrane viscosity of liposomes was checked. An increase in viscosity was observed for DPPC and DMPC near the phase-transition temperature. Ho-phospholipid complexes could be used as sensors of local membrane viscosity in NMR and MRI technologies.

Keyphrases

magnetic resonance
fatty acid
high resolution
solid state
drug delivery
magnetic resonance imaging
contrast enhanced
pi k akt
computed tomography
mass spectrometry
drug release
cell proliferation
low cost