Efficacy and safety of cavernous sinus medial wall resection in pituitary adenoma surgery: a systematic review and a single-arm meta-analysis.
Julia Pereira Muniz PontesOfonime Chantal Udoma-UdofaJéssica Sales de OliveiraAnna Laura Lima LarciprettiCaroline Serafim DagostinFernando Cotrim GomesGabriela Borges NagerMatheus de Andrade BannachPublished in: Pituitary (2023)
The cavernous sinus was ruled out, proving the MWCS excision is safe. Limiting population selection to Knosp 3A or lower enhanced GTR frequencies and lowered recurrence, according to subgroup analyses. This meta-analysis shows that MWCS resection can be a beneficial treatment option for pituitary tumors, when there is no macroscopic medial wall invasion and careful patient selection is done, especially for GH- and ACTH-producing tumors that can cause life-threatening metabolic changes.