Notch down-regulation and inflammatory cytokines and RANKL overexpression involvement in peri-implant mucositis and peri-implantitis: A cross-sectional study.

Iva Milinkovic Ana Djinic Krasavcevic Nadja Nikolic Zoran Aleksić Jelena ČarkićMarija JezdicSasha JankovicJelena M Milasin

Published in: Clinical oral implants research (2021)

The combined effect of Notch 1 down-regulation and elevated expression of some key inflammation modulators might result in osteoclast activity increase and subsequent osteolysis in peri-implantitis.

Keyphrases

cell proliferation
poor prognosis
oxidative stress
bone loss
small molecule
physical activity
radiation induced
transcription factor
risk factors
nuclear factor
toll like receptor
inflammatory response
chemotherapy induced