Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Xiaohui JinYixin YuanChi ZhangYong ZhouYue SongZhanyong WeiGaiping ZhangPublished in: Journal of veterinary science (2020)
These findings indicated that PPV NS1 protein induced the up-regulated of IL-6 expression through activating the TLR2 and NF-κB signaling pathways. In conclusion, these findings provide a new avenue to study the innate immune mechanism of PPV infection.
Keyphrases
- signaling pathway
- pi k akt
- innate immune
- toll like receptor
- induced apoptosis
- epithelial mesenchymal transition
- inflammatory response
- binding protein
- dengue virus
- immune response
- poor prognosis
- nuclear factor
- protein protein
- lps induced
- amino acid
- diabetic rats
- oxidative stress
- drug induced
- zika virus
- cell proliferation
- long non coding rna