Effect of atomoxetine on ADHD-pain hypersensitization comorbidity in 6-OHDA lesioned mice.

Wahiba SifeddineSaadia Ba-M'hamedMarc LandryMohammed Bennis

Published in: Pharmacological reports : PR (2023)

These findings demonstrated that when administered chronically, atomoxetine has a significant effect on ADHD-associated pain hypersensitization, likely mediated by both α- and β-adrenergic and D2/D3 dopaminergic receptors, and suggest new indications for atomoxetine that will need to be confirmed by well-designed clinical trials.

Keyphrases

attention deficit hyperactivity disorder
chronic pain
autism spectrum disorder
clinical trial
pain management
working memory
neuropathic pain
randomized controlled trial
type diabetes
high fat diet induced
insulin resistance
phase iii
open label