Cluster Analysis of Cardiovascular Phenotypes in Patients With Type 2 Diabetes and Established Atherosclerotic Cardiovascular Disease: A Potential Approach to Precision Medicine.

Abhinav SharmaYinggan ZhengJustin A EzekowitzCynthia M WesterhoutJacob A UdellShaun G GoodmanPaul W ArmstrongJohn B BuseJennifer B GreenRobert G JosseKeith D KaufmanDarren K McGuireGiuseppe AmbrosioLee-Ming ChuangRenato D LopesEric D PetersonRury R Holman

Published in: Diabetes care (2021)

In patients with T2DM and ASCVD, cluster analysis identified four clinically distinct groups. Further cardiovascular phenotyping is warranted to inform patient care and optimize clinical trial designs.

Keyphrases

cardiovascular disease
clinical trial
high throughput
type diabetes
randomized controlled trial
double blind
phase ii
cardiovascular events
coronary artery disease
skeletal muscle