Genomic Risk Score for Advanced Osteoarthritis in Older Adults.

Paul LacazeYuanyuan WangGalina PolekhinaAndrew BakshiMoeen RiazAlice OwenAngus FranksJawad AbidiJane TillerJohn McNeilFlavia Cicuttini

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2022)

PRS have the potential to improve prevention of severe knee and hip OA by providing a personalized approach and identifying individuals who may benefit from early intervention.

Keyphrases

knee osteoarthritis
randomized controlled trial
total knee arthroplasty
physical activity
copy number
early onset
rheumatoid arthritis
total hip arthroplasty
human health
anterior cruciate ligament reconstruction
gene expression
drug induced