Clinical Course, Antifungal Susceptibility, and Genomic Sequencing of Trichophyton indotineae.
Avrom S CaplanGabrielle C ToddYanChun ZhuMichelle SikoraChristine C AkohJeannette JakusShari R LipnerKayla Babbush GraberKaren P AckerAyana E MoralesRebecca M Marrero RolónLars F WestbladeMaira FonsecaAbigail ClineJeremy A W GoldShawn R LockhartDallas J SmithTom ChillerWilliam G GreendykeSwati R ManjariNilesh K BanavaliSudha ChaturvediPublished in: JAMA dermatology (2024)
The results of this case series suggest that disease severity, diagnostic delays, and lack of response to typically used doses and durations of antifungals for tinea were common in this primarily immunocompetent patient cohort with T indotineae, consistent with published data. Itraconazole was generally effective, and the acquisition of infection was likely in Bangladesh.