TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability.

Xintian ChenHongmei YongMiaolei ChenChuyin DengPengfei WangSufang ChuMinle LiPingfu HouJun-Nian ZhengZhongwei LiJin Bai

Published in: Journal of experimental & clinical cancer research : CR (2023)

The findings from this study reveal a novel pathway through which TRIM21 inhibits the lipid metabolism process of RCC and shed light on the development of targeted metabolic treatment and prognosis diagnosis of RCC.

Keyphrases

genome wide
single cell
type diabetes
fatty acid
amino acid
adipose tissue
small molecule
insulin resistance
combination therapy