Genetic alteration of SLCO1B3 defines constitutional indocyanine green excretory defect in patients who underwent hepatectomy.

Meguri TanimotoYujiro NishiokaYoshinori InagakiTakashi KokudoTakeaki IshizawaJunichi AritaNobuhisa AkamatsuJunichi KanekoKiyoshi Hasegawa

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2024)

Constitutional ICG excretory defects may be defined by the complete absence of OATP1B3 expression. The modified ALBI grade and 99mTc-GSA hepatic scintigraphy were useful for detecting constitutional ICG excretory defects.

Keyphrases

end stage renal disease
ejection fraction
fluorescence imaging
newly diagnosed
poor prognosis
prognostic factors
genome wide
dna methylation
gene expression
patient reported outcomes
pet ct
photodynamic therapy