Correlations between Kidney and Heart Function Bioindicators and the Expressions of Toll-Like, ACE2, and NRP-1 Receptors in COVID-19.
Rabab Hussain SultanBasem H ElesawyTarek M AliMaged AbdallahHebatallah Hany AssalAmr E AhmedOsama M AhmedPublished in: Vaccines (2022)
Our study concluded that expression levels for TLR2, TLR4, ACE2, and NRP-1 mRNA in both severe and moderate patients were positively correlated with renal biomarkers and cardiac enzymes. Innate immune markers can be important because they correlate with the severity of illness in COVID-19.
Keyphrases
- coronavirus disease
- sars cov
- innate immune
- toll like receptor
- end stage renal disease
- inflammatory response
- immune response
- newly diagnosed
- ejection fraction
- poor prognosis
- angiotensin converting enzyme
- chronic kidney disease
- angiotensin ii
- heart failure
- prognostic factors
- early onset
- binding protein
- high intensity
- atrial fibrillation
- nuclear factor
- drug induced