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Comparison of anti-fracture effectiveness of zoledronate, ibandronate and alendronate versus denosumab in a registry-based cohort study.

Judith Everts-GraberHarald BonelDaniel LehmannBrigitta GahlHansJörg HäuselmannUeli StuderHans-Rudolf ZiswilerStephan ReichenbachThomas Lehmann
Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2023)
When adjusting for disease severity, denosumab was associated with significantly greater risk reduction than alendronate and ibandronate for vertebral fractures. No difference in fracture risk reduction was found between zoledronate and denosumab.
Keyphrases
  • bone mineral density
  • giant cell
  • postmenopausal women
  • randomized controlled trial
  • systematic review
  • hip fracture