eQTL Set-Based Association Analysis Identifies Novel Susceptibility Loci for Barrett Esophagus and Esophageal Adenocarcinoma.
Xiaoyu WangPuya GharahkhaniDavid M LevineRebecca C FitzgeraldInes GockelDouglas A CorleyHarvey A RischLeslie BernsteinWong-Ho ChowLynn OnstadNicholas J ShaheenJesper LagergrenLaura J HardieAnna H WuPaul David Peter PharoahGeoffrey LiuLesley Ann AndersonPrasad G IyerMarilie D GammonCarlos CaldasWeimin YeHugh BarrPaul MoayyediRebecca HarrisonR G Peter WatsonStephen E AttwoodLaura ChegwiddenSharon B LoveDavid MacDonaldJohn deCaesteckerHans PrenenKatja OttSusanne MoebusMarino VeneritoHauke LangRupert MayershoferMichael KnappLothar VeitsChristian GergesJosef WeismüllerMatthias ReehMarkus Maria NöthenJakob R IzbickiHendrik MannerHorst NeuhausThomas RöschAnne C BöhmerArnulf H HölscherMario AndersOliver PechBrigitte SchumacherClaudia SchmidtThomas SchmidtTania NoderDietmar LorenzMichael ViethAndrea MayTimo HessNicole KreuserJessica BeckerChristian EllIan P M TomlinsonClaire PallesJanusz A JankowskiDavid C WhitemanStuart MacgregorJohannes SchumacherThomas L VaughanMatthew F BuasJames Y DaiPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2022)
This study expanded the pool of genetic susceptibility loci for EAC and BE, suggesting the potential of the eQTL set-based genetic association approach as an alternative method for TWAS analysis.