Carlos Caldas

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 62

Top Topics

Early Breast Cancer

Dna Methylation

Top Venues

Nature communications

NPJ breast cancer

JCO precision oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Danh-Tai Hoang, Gal Dinstag, Eldad David Shulman, Leandro C Hermida, Doreen S Ben-Zvi, Efrat Elis, Katherine Caley, Stephen-John Sammut, Sanju Sinha, Neelam Sinha, Christopher H Dampier, Chani Stossel, Tejas Patil, Arun Rajan, Wiem Lassoued, Julius Strauss, Shania Bailey, Clint T Allen, Jason Mark Redman, Tuvik Beker, Peng Jiang, Talia Golan, Scott Wilkinson, Adam G Sowalsky, Sharon R Pine, Carlos Caldas, James L Gulley, Kenneth D Aldape, Ranit Aharonov, Eric A Stone, Eytan Ruppin
A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics. Nature cancer (2024)
Stephen-John Sammut, Jacob D Galson, Ralph Minter, Bo Sun, Suet-Feung Chin, Leticia De Mattos-Arruda, Donna K Finch, Sebastian Schätzle, Jorge Dias, Oscar M Rueda, Joan Seoane, Jane Osbourn, Carlos Caldas, Rachael J M Bashford-Rogers
Predictability of B cell clonal persistence and immunosurveillance in breast cancer. Nature immunology 25 (5) (2024)
Jia Wern Pan, Zi-Ching Tan, Pei-Sze Ng, Muhammad Mamduh Ahmad Zabidi, Putri Nur Fatin, Jie-Ying Teo, Siti Norhidayu Hasan, Tania Islam, Li-Ying Teoh, Suniza Jamaris, Mee-Hoong See, Cheng-Har Yip, Pathmanathan Rajadurai, Lai-Meng Looi, Nur Aishah Mohd Taib, Oscar M Rueda, Carlos Caldas, Suet-Feung Chin, Joanna Lim, Soo-Hwang Teo
Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancer. NPJ breast cancer 10 (1) (2024)
Jia Wern Pan, Zi-Ching Tan, Pei-Sze Ng, Muhammad Mamduh Ahmad Zabidi, Putri Nur Fatin, Jie-Ying Teo, Siti Norhidayu Hasan, Tania Islam, Li-Ying Teoh, Suniza Jamaris, Mee-Hoong See, Cheng-Har Yip, Pathmanathan Rajadurai, Lai-Meng Looi, Nur Aishah Mohd Taib, Oscar M Rueda, Carlos Caldas, Suet-Feung Chin, Joanna Lim, Soo-Hwang Teo
Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancer. NPJ breast cancer 10 (1) (2024)
Danh-Tai Hoang, Gal Dinstag, Eldad David Shulman, Leandro C Hermida, Doreen S Ben-Zvi, Efrat Elis, Katherine Caley, Stephen-John Sammut, Sanju Sinha, Neelam Sinha, Christopher H Dampier, Chani Stossel, Tejas Patil, Arun Rajan, Wiem Lassoued, Julius Strauss, Shania Bailey, Clint T Allen, Jason Mark Redman, Tuvik Beker, Peng Jiang, Talia Golan, Scott Wilkinson, Adam G Sowalsky, Sharon R Pine, Carlos Caldas, James L Gulley, Kenneth D Aldape, Ranit Aharonov, Eric A Stone, Eytan Ruppin
A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics. Nature cancer (2024)
Stephen-John Sammut, Jacob D Galson, Ralph Minter, Bo Sun, Suet-Feung Chin, Leticia De Mattos-Arruda, Donna K Finch, Sebastian Schätzle, Jorge Dias, Oscar M Rueda, Joan Seoane, Jane Osbourn, Carlos Caldas, Rachael J M Bashford-Rogers
Predictability of B cell clonal persistence and immunosurveillance in breast cancer. Nature immunology 25 (5) (2024)
Riccardo Masina, Carlos Caldas
Precision Cancer Medicine 2.0-Oncology in the postgenomic era. Molecular oncology (2024)
Stephen-John Sammut, Jacob D Galson, Ralph Minter, Bo Sun, Suet-Feung Chin, Leticia De Mattos-Arruda, Donna K Finch, Sebastian Schätzle, Jorge Dias, Oscar M Rueda, Joan Seoane, Jane Osbourn, Carlos Caldas, Rachael J M Bashford-Rogers
Predictability of B cell clonal persistence and immunosurveillance in breast cancer. Nature immunology 25 (5) (2024)
Jia Wern Pan, Zi-Ching Tan, Pei-Sze Ng, Muhammad Mamduh Ahmad Zabidi, Putri Nur Fatin, Jie-Ying Teo, Siti Norhidayu Hasan, Tania Islam, Li-Ying Teoh, Suniza Jamaris, Mee-Hoong See, Cheng-Har Yip, Pathmanathan Rajadurai, Lai-Meng Looi, Nur Aishah Mohd Taib, Oscar M Rueda, Carlos Caldas, Suet-Feung Chin, Joanna Lim, Soo-Hwang Teo
Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancer. NPJ breast cancer 10 (1) (2024)
Stephen-John Sammut, Jacob D Galson, Ralph Minter, Bo Sun, Suet-Feung Chin, Leticia De Mattos-Arruda, Donna K Finch, Sebastian Schätzle, Jorge Dias, Oscar M Rueda, Joan Seoane, Jane Osbourn, Carlos Caldas, Rachael J M Bashford-Rogers
Predictability of B cell clonal persistence and immunosurveillance in breast cancer. Nature immunology 25 (5) (2024)
Angela Santonja, Wendy N Cooper, Matthew D Eldridge, Paul A W Edwards, James A Morris, Abigail R Edwards, Hui Zhao, Katrin Heider, Dominique-Laurent Couturier, Aadhitthya Vijayaraghavan, Paulius Mennea, Emma-Jane Ditter, Christopher G Smith, Chris Boursnell, Raquel Manzano Garcia, Oscar M Rueda, Emma Beddowes, Heather Biggs, Stephen-John Sammut, Nitzan Rosenfeld, Carlos Caldas, Jean E Abraham, Davina Gale
Comparison of tumor-informed and tumor-naïve sequencing assays for ctDNA detection in breast cancer. EMBO molecular medicine (2023)
Peter A Kreuzaler, Paolo Inglese, Avinash D Ghanate, Ersa Gjelaj, Vincen Wu, Yulia Panina, Andres Mendez-Lucas, Catherine MacLachlan, Neill Patani, Catherine B Hubert, Helen Huang, Gina Greenidge, Oscar M Rueda, Adam J Taylor, Evdoxia Karali, Emine Kazanc, Amy R Spicer-Hadlington, Alex Dexter, Wei Lin, Daria Thompson, Mariana Silva Dos Santos, Enrica Calvani, Nathalie M Legrave, James K Ellis, Wendy Greenwood, Mary Green, Emma Nye, Emma Still, null null, Simon T Barry, Richard J A Goodwin, Alejandra Bruna, Carlos Caldas, James I MacRae, Luiz Pedro Sório de Carvalho, George Poulogiannis, Greg McMahon, Zoltán Takáts, Josephine Bunch, Mariia O Yuneva
Vitamin B 5 supports MYC oncogenic metabolism and tumor progression in breast cancer. Nature metabolism (2023)
Ha-Linh Nguyen, Tatjana Geukens, Marion Maetens, Samuel A J R Aparicio, Ayse Bassez, Åke Borg, Jane Brock, Annegien Broeks, Carlos Caldas, Fatima Cardoso, Maxim De Schepper, Mauro Delorenzi, Caroline A Drukker, Annuska M Glas, Andrew R Green, Edoardo Isnaldi, Jórunn Eyfjörð, Hazem Khout, Stian Knappskog, Savitri Krishnamurthy, Sunil R Lakhani, Anita Langerod, John W M Martens, Amy E McCart Reed, Leigh Murphy, Stefan Naulaerts, Serena Nik-Zainal, Ines Nevelsteen, Patrick Neven, Martine J Piccart, Coralie Poncet, Kevin Punie, Colin Purdie, Emad A Rakha, Andrea Richardson, Emiel Rutgers, Anne-Vincent Salomon, Peter Thomas Simpson, Marjanka K Schmidt, Christos Sotiriou, Paul N Span, Kiat Tee Benita Tan, Alastair Thompson, Stefania Tommasi, Karen Van Baelen, Marc Van de Vijver, Steven Van Laere, Laura van 't Veer, Giuseppe Viale, Alain Viari, Hanne Vos, Anke T Witteveen, Hans P M W Wildiers, Giuseppe Floris, Abhishek Dinkarnath Garg, Ann Smeets, Diether Lambrechts, Elia Mario Biganzoli, François Richard, Christine Desmedt
Obesity-associated changes in molecular biology of primary breast cancer. Nature communications 14 (1) (2023)
Eytan Ruppin, Danh-Tai Hoang, Gal Dinstag, Leandro Hermida, Doreen S Ben-Zvi, Efrat Elis, Katherine Caley, Stephen-John Sammut, Sanju Sinha, Neelam Sinha, Christopher H Dampier, Chani Stossel, Tejas Patil, Arun Rajan, Wiem Lassoued, Julius Strauss, Shania Bailey, Clint T Allen, Jason Redman, Tuvik Beker, Peng Jiang, Talia Golan, Scott Wilkinson, Adam G Sowalsky, Sharon R Pine, Carlos Caldas, James L Gulley, Kenneth D Aldape, Ranit Aharonov, Eric Stone
Prediction of cancer treatment response from histopathology images through imputed transcriptomics. Research square (2023)
Benedetta Pellegrino, Andrea Herencia-Ropero, Alba Llop-Guevara, Flaminia Pedretti, Alejandro Moles-Fernández, Cristina Viaplana, Guillermo Villacampa, Marta Guzmán, Olga Rodríguez, Judit Grueso, Jose Jiménez, Enrique J Arenas, Andrea Degasperi, Joao M L Dias, Josep V Forment, Lenka Oplustil O'Connor, Olivier Déas, Stefano Cairo, Yinghui Zhou, Antonino Musolino, Carlos Caldas, Serena Nik-Zainal, Robert B Clarke, Paolo G Nuciforo, Orland Díez, Xavier Serres-Créixams, Vicente Peg, Martín Espinosa-Bravo, Teresa Macarulla, Ana Oaknin, Joaquin Mateo, Joaquín Arribas, Rodrigo Dienstmann, Meritxell Bellet-Ezquerra, Mafalda Oliveira, Cristina Saura, Sara Gutiérrez-Enríquez, Judith Balmaña, Violeta Serra
Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification. Cancer research 82 (8) (2022)
Violeta Serra, Anderson T Wang, Marta Castroviejo-Bermejo, Urszula M Polanska, Marta Palafox, Andrea Herencia-Ropero, Gemma N Jones, Zhongwu Lai, Joshua Armenia, Filippos Michopoulos, Alba Llop-Guevara, Rachel Brough, Aditi Gulati, Stephen J Pettitt, Krishna C Bulusu, Jenni Nikkilä, Zena Wilson, Adina M Hughes, Paul W G Wijnhoven, Ambar Ahmed, Alejandra Bruna, Albert Gris-Oliver, Marta Guzman, Olga Rodríguez, Judit Grueso, Joaquín Arribas, Javier Cortes, Cristina Saura, Alan Lau, Susan E Critchlow, Brian Dougherty, Carlos Caldas, Gordon B Mills, J Carl Barrett, Josep V Forment, Elaine B Cadogan, Christopher J Lord, Cristina Cruz, Judith Balmaña, Lenka Oplustil O'Connor
Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (20) (2022)
Lizelle Correia, Ramiro Magno, Joana M Xavier, Bernardo P de Almeida, Isabel Duarte, Filipa Esteves, Marinella Ghezzo, Matthew D Eldridge, Chong Sun, Astrid Bosma, Lorenza Mittempergher, Ana Marreiros, René Bernards, Carlos Caldas, Suet-Feung Chin, Ana-Teresa Maia
Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant. NPJ breast cancer 8 (1) (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
David Tamborero, Rodrigo Dienstmann, Maan Haj Rachid, Jorrit Boekel, Adrià López-Fernández, Markus Jonsson, Ali Razzak, Irene Braña, Luigi De Petris, Jeffrey Yachnin, Richard D Baird, Yohann Loriot, Christophe Massard, Patricia Martin-Romano, Frans Opdam, Richard F Schlenk, Claudio Vernieri, Michele Masucci, Xenia Villalobos, Elena Chavarria, null null, Judith Balmaña, Giovanni Apolone, Carlos Caldas, Jonas Bergh, Ingemar Ernberg, Stefan Fröhling, Elena Garralda, Claes Karlsson, Josep Tabernero, Emile E Voest, Jordi Rodon, Janne Lehtiö
The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology. Nature cancer 3 (2) (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
Marta Palafox, Laia Monserrat, Meritxell Bellet, Guillermo Villacampa, Nuria Lopez-Bigas, Mafalda Oliveira, Fara Brasó-Maristany, Nusaibah Ibrahimi, Srinivasaraghavan Kannan, Leonardo Mina, Maria Teresa Herrera-Abreu, Andreu Òdena, Mònica Sánchez-Guixé, Marta Capelán, Analía Azaro, Alejandra Bruna, Olga Rodríguez, Marta Guzmán, Judit Grueso, Cristina Viaplana, Javier Hernández-Losa, Faye Su, Kui Lin, Robert B Clarke, Carlos Caldas, Joaquín Arribas, Stefan Michiels, Alicia García-Sanz, Nicholas C Turner, Aleix Prat, Paolo G Nuciforo, Rodrigo Dienstmann, Chandra S Verma, Núria López-Bigas, Maurizio Scaltriti, Monica Arnedos, Cristina Saura, Violeta Serra
Author Correction: High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER + breast cancer. Nature communications 13 (1) (2022)
Filipe Correia Martins, Dominique-Laurent Couturier, Ines de Santiago, Carolin Margarethe Sauer, Maria Vias, Mihaela Angelova, Deborah Sanders, Anna Piskorz, James Hall, Karen Hosking, Anumithra Amirthanayagam, Sabina Cosulich, Larissa S Carnevalli, Barry R Davies, Thomas B K Watkins, Ionut-Gabriel Funingana, Helen Bolton, Krishnayan Haldar, John Latimer, Peter Baldwin, Robin Crawford, Matthew D Eldridge, Bristi Basu, Mercedes Jimenez-Linan, Andrew W Mcpherson, Nicholas McGranahan, Kevin Litchfield, Sohrab P Shah, Iain A McNeish, Carlos Caldas, Gerard I Evan, Charles Swanton, James D Brenton
Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer. Nature communications 13 (1) (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
Lorenzo Gerratana, Jean-Yves Pierga, James M Reuben, Andrew A Davis, Firas H Wehbe, Luc Dirix, Tanja Fehm, Franco Nolé, Rafael Gisbert-Criado, Dimitrios Mavroudis, Salvatore Grisanti, Jose A Garcia-Saenz, Justin Stebbing, Carlos Caldas, Paola Gazzaniga, Luis Manso, Rita Zamarchi, Marta Bonotto, Angela Fernandez de Lascoiti, Leticia De Mattos-Arruda, Michail Ignatiadis, Maria-Teresa Sandri, Daniele Generali, Carmine De Angelis, Sarah-Jane Dawson, Wolfgang Janni, Vicente Carañana, Sabine Riethdorf, Erich-Franz Solomayer, Fabio Puglisi, Mario Giuliano, Klaus Pantel, Francois-Clement Bidard, Massimo Cristofanilli
Modeling the Prognostic Impact of Circulating Tumor Cells Enumeration in Metastatic Breast Cancer for Clinical Trial Design Simulation. The oncologist 27 (7) (2022)
Marta Palafox, Laia Monserrat, Meritxell Bellet, Guillermo Villacampa, Nuria Lopez-Bigas, Mafalda Oliveira, Fara Brasó-Maristany, Nusaibah Ibrahimi, Srinivasaraghavan Kannan, Leonardo Mina, Maria Teresa Herrera-Abreu, Andreu Òdena, Mònica Sánchez-Guixé, Marta Capelán, Analía Azaro, Alejandra Bruna, Olga Rodríguez, Marta Guzmán, Judit Grueso, Cristina Viaplana, Javier Hernández-Losa, Faye Su, Kui Lin, Robert B Clarke, Carlos Caldas, Joaquín Arribas, Stefan Michiels, Alicia García-Sanz, Nicholas C Turner, Aleix Prat, Paolo G Nuciforo, Rodrigo Dienstmann, Chandra S Verma, Núria López-Bigas, Maurizio Scaltriti, Monica Arnedos, Cristina Saura, Violeta Serra
High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER + breast cancer. Nature communications 13 (1) (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
Xiaoyu Wang, Puya Gharahkhani, David M Levine, Rebecca C Fitzgerald, Ines Gockel, Douglas A Corley, Harvey A Risch, Leslie Bernstein, Wong-Ho Chow, Lynn Onstad, Nicholas J Shaheen, Jesper Lagergren, Laura J Hardie, Anna H Wu, Paul David Peter Pharoah, Geoffrey Liu, Lesley Ann Anderson, Prasad G Iyer, Marilie D Gammon, Carlos Caldas, Weimin Ye, Hugh Barr, Paul Moayyedi, Rebecca Harrison, R G Peter Watson, Stephen E Attwood, Laura Chegwidden, Sharon B Love, David MacDonald, John deCaestecker, Hans Prenen, Katja Ott, Susanne Moebus, Marino Venerito, Hauke Lang, Rupert Mayershofer, Michael Knapp, Lothar Veits, Christian Gerges, Josef Weismüller, Matthias Reeh, Markus Maria Nöthen, Jakob R Izbicki, Hendrik Manner, Horst Neuhaus, Thomas Rösch, Anne C Böhmer, Arnulf H Hölscher, Mario Anders, Oliver Pech, Brigitte Schumacher, Claudia Schmidt, Thomas Schmidt, Tania Noder, Dietmar Lorenz, Michael Vieth, Andrea May, Timo Hess, Nicole Kreuser, Jessica Becker, Christian Ell, Ian P M Tomlinson, Claire Palles, Janusz A Jankowski, David C Whiteman, Stuart Macgregor, Johannes Schumacher, Thomas L Vaughan, Matthew F Buas, James Y Dai
eQTL Set-Based Association Analysis Identifies Novel Susceptibility Loci for Barrett Esophagus and Esophageal Adenocarcinoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 31 (9) (2022)
Esther Danenberg, Helen Bardwell, Vito R T Zanotelli, Elena Provenzano, Suet-Feung Chin, Oscar M Rueda, Andrew R Green, Emad Rakha, Samuel A J R Aparicio, Ian O Ellis, Bernd Bodenmiller, Carlos Caldas, H Raza Ali
Breast tumor microenvironment structures are associated with genomic features and clinical outcome. Nature genetics 54 (5) (2022)
Tom van den Bosch, Oscar M Rueda, Carlos Caldas, Louis Vermeulen, Daniël M Miedema
Copy number heterogeneity identifies ER+ breast cancer patients that do not benefit from adjuvant endocrine therapy. British journal of cancer 127 (7) (2022)
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Isabelle Durand Zaleski, Geert Frederix, Lars-Åke Levin, Charles G Mullighan, Reinhard Buttner, Trevor J Pugh, Sean M Grimmond, Carlos Caldas, Fabrice Andre, Ilse Custers, Elias Campo, Hans van Snellenberg, Anna Schuh, Hidewaki Nakagawa, Christof von Kalle, Torsten Haferlach, Stefan Fröhling, Vaidehi Jobanputra
Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care. JCO precision oncology 6 (2022)
Pei Sze Ng, Jia Wern Pan, Muhammad Mamduh Ahmad Zabidi, Pathmanathan Rajadurai, Cheng Har Yip, Oscar M Rueda, Alison M Dunning, Antonis C Antoniou, Douglas F Easton, Carlos Caldas, Suet-Feung Chin, Soo-Hwang Teo
Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses. NPJ breast cancer 7 (1) (2021)
Hendrik J Kuiken, Sabin Dhakal, Laura M Selfors, Chandler M Friend, Tian Zhang, Maurizio Callari, Ron C J Schackmann, G Kenneth Gray, Jett Crowdis, Hyo-Eun C Bhang, Timour Baslan, Frank Stegmeier, Steven P Gygi, Carlos Caldas, Joan S Brugge
Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts. Oncogene (2021)
Jonathan C M Wan, Katrin Heider, Davina Gale, Suzanne Murphy, Eyal Fisher, Florent Mouliere, Andrea Ruiz-Valdepenas, Angela Santonja, James Morris, Dineika Chandrananda, Andrea Marshall, Andrew B Gill, Pui Ying Chan, Emily Barker, Gemma Young, Wendy N Cooper, Irena Hudecova, Francesco Marass, Richard Mair, Kevin M Brindle, Grant D Stewart, Jean E Abraham, Carlos Caldas, Doris M Rassl, Robert C Rintoul, Constantine Alifrangis, Mark Ross Middleton, Ferdia A Gallagher, Christine Parkinson, Amer Durrani, Ultan McDermott, Christopher G Smith, Charles E Massie, Philippa Corrie, Nitzan Rosenfeld
ctDNA monitoring using patient-specific sequencing and integration of variant reads. Science translational medicine 12 (548) (2021)
Karen D Howarth, Tashfina Mirza, Susanna L Cooke, Suet-Feung Chin, Jessica C Pole, Ernest Turro, Matthew D Eldridge, Raquel Manzano Garcia, Oscar M Rueda, Chris Boursnell, Jean E Abraham, Carlos Caldas, Paul A W Edwards
NRG1 fusions in breast cancer. Breast cancer research : BCR 23 (1) (2021)
Dimitra Georgopoulou, Maurizio Callari, Oscar M Rueda, Abigail Shea, Alistair Martin, Agnese Giovannetti, Fatime Qosaj, Ali Dariush, Suet-Feung Chin, Larissa S Carnevalli, Elena Provenzano, Wendy Greenwood, Giulia Lerda, Elham Esmaeilishirazifard, Martin O'Reilly, Violeta Serra, Dario Bressan, null null, Gordon B Mills, H Raza Ali, Sabina S Cosulich, Gregory J Hannon, Alejandra Bruna, Carlos Caldas
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response. Nature communications 12 (1) (2021)
Albert Gris-Oliver, Yasir H Ibrahim, Martín A Rivas, Celina García-García, Mònica Sánchez-Guixé, Fiorella Ruiz-Pace, Cristina Viaplana, José M Pérez-García, Antonio Llombart-Cussac, Judit Grueso, Mireia Parés, Marta Guzmán, Olga Rodríguez, Pilar Anton, Patricia Cozar, Maria Teresa Calvo, Alejandra Bruna, Joaquín Arribas, Carlos Caldas, Rodrigo Dienstmann, Paolo Nuciforo, Mafalda Oliveira, Javier Cortes, Violeta Serra
PI3K activation promotes resistance to eribulin in HER2-negative breast cancer. British journal of cancer 124 (9) (2021)
Long V Nguyen, Carlos Caldas
Functional genomics approaches to improve pre-clinical drug screening and biomarker discovery. EMBO molecular medicine 13 (9) (2021)
Leticia De Mattos-Arruda, Javier Cortes, Juan Blanco-Heredia, Daniel Guimarães Tiezzi, Guillermo Villacampa, Samuel Gonçalves-Ribeiro, Laia Paré, Carla Anjos Souza, Vanesa Ortega, Stephen-John Sammut, Pol Cusco, Roberta Fasani, Suet-Feung Chin, Jose Perez-Garcia, Rodrigo Dienstmann, Paolo Nuciforo, Patricia Villagrasa, Isabel T Rubio, Aleix Prat, Carlos Caldas
The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers. NPJ breast cancer 7 (1) (2021)
Karsten Bach, Sara Pensa, Marija Zarocsinceva, Katarzyna Kania, Julie Stockis, Silvain Pinaud, Kyren A Lazarus, Mona Shehata, Bruno M Simões, Alice R Greenhalgh, Sacha J Howell, Robert B Clarke, Carlos Caldas, Timotheus Y F Halim, John C Marioni, Walid T Khaled
Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors. Nature communications 12 (1) (2021)
Helena Earl, Louise Hiller, Anne-Laure Vallier, Shrushma Loi, Karen McAdam, Luke Hughes-Davies, Daniel W Rea, Donna Howe, Kerry Raynes, Helen B Higgins, Maggie Wilcox, Chris Plummer, Betania Mahler-Araujo, Elena Provenzano, Anita Chhabra, Sophie Gasson, Claire Balmer, Jean E Abraham, Carlos Caldas, Peter S Hall, Bethany Shinkins, Christopher McCabe, Claire T Hulme, David Miles, Andrew M Wardley, David A Cameron, Janet A Dunn
Six versus 12 months' adjuvant trastuzumab in patients with HER2-positive early breast cancer: the PERSEPHONE non-inferiority RCT. Health technology assessment (Winchester, England) 24 (40) (2021)
Stephen-John Sammut, Mireia Crispin-Ortuzar, Suet-Feung Chin, Elena Provenzano, Helen A Bardwell, Wenxin Ma, Wei Cope, Ali Dariush, Sarah-Jane Dawson, Jean E Abraham, Janet Dunn, Louise Hiller, Jeremy Thomas, David A Cameron, John M S Bartlett, Larry Hayward, Paul David Peter Pharoah, Florian Markowetz, Oscar M Rueda, Helena M Earl, Carlos Caldas
Multi-omic machine learning predictor of breast cancer therapy response. Nature (2021)
Safae Terrisse, Lisa Derosa, Valerio Iebba, François Ghiringhelli, Ines Vaz-Luis, Guido Kroemer, Marine Fidelle, Stergios Christodoulidis, Nicola Segata, Andrew Maltez Thomas, Anne-Laure Martin, Aude Sirven, Sibille Everhard, Fanny Aprahamian, Nitharsshini Nirmalathasan, Romy Aarnoutse, Marjolein Smidt, Janine Ziemons, Carlos Caldas, Sibylle Loibl, Carsten Denkert, Sylvere Durand, Claudia Iglesias, Filippo Pietrantonio, Bertrand Routy, Fabrice André, Edoardo Pasolli, Suzette Delaloge, Laurence Zitvogel
Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment. Cell death and differentiation 28 (9) (2021)
Mary Luz Uribe, Maik Dahlhoff, Rajbir Nath Batra, Nishanth Belugali Nataraj, Yuya Haga, Diana Drago-Garcia, Ilaria Marrocco, Arunachalam Sekar, Soma Ghosh, Itay Vaknin, Sacha Lebon, Lior Kramarski, Yasuo Tsutsumi, Inpyo Choi, Oscar M Rueda, Carlos Caldas, Yosef Yarden
TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis. Science signaling 14 (688) (2021)
Samuel Terkper Ahuno, Anna-Lisa Doebley, Thomas U Ahearn, Joel Yarney, Nicholas Titiloye, Nancy Hamel, Ernest Adjei, Joe-Nat Clegg-Lamptey, Lawrence Edusei, Baffour Awuah, Xiaoyu Song, Verna Vanderpuye, Mustapha Abubakar, Máire A Duggan, Daniel G Stover, Kofi Nyarko, Timothy J Whelan, Frances S Aitpillah, Daniel Ansong, Kevin L Gardner, Felix Andy Boateng, Anne M Bowcock, Carlos Caldas, William D Foulkes, Seth Wiafe, Beatrice Wiafe-Addai, Montserrat Garcia-Closas, Alexander Kwarteng, Gavin Ha, Jonine D Figueroa, Paz Polak, null null
Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa. NPJ precision oncology 5 (1) (2021)
Rajbir Nath Batra, Aviezer Lifshitz, Ana Tufegdzic Vidakovic, Suet-Feung Chin, Ankita Sati-Batra, Stephen-John Sammut, Elena Provenzano, H Raza Ali, Ali Dariush, Alejandra Bruna, Leigh Murphy, Arnie Purushotham, Ian O Ellis, Andrew Green, Francine E Garrett-Bakelman, Christopher E Mason, Ari M Melnick, Samuel A J R Aparicio, Oscar M Rueda, Amos Tanay, Carlos Caldas
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation. Nature communications 12 (1) (2021)
Tomo Osako, Hakwoo Lee, Gulisa Turashvili, Derek Chiu, Steven McKinney, Stacey E P Joosten, Darcy Wilkinson, Torsten O Nielsen, Wilbert Zwart, Joanne T Emerman, Connie J Eaves, Carlos Caldas, Samuel A J R Aparicio
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Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer. Science translational medicine 11 (504) (2020)
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Caring for patients with cancer in the COVID-19 era. Nature medicine 26 (5) (2020)
David Tamborero, Rodrigo Dienstmann, Maan Haj Rachid, Jorrit Boekel, Richard D Baird, Irene Braña, Luigi De Petris, Jeffrey Yachnin, Christophe Massard, Frans L Opdam, Richard Schlenk, Claudio Vernieri, Elena Garralda, Michele Masucci, Xenia Villalobos, Elena Chavarria, null null, Fabien Calvo, Stefan Fröhling, Alexander Eggermont, Giovanni Apolone, Emile E Voest, Carlos Caldas, Josep Tabernero, Ingemar Ernberg, Jordi Rodon, Janne Lehtiö
Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal. Nature medicine 26 (7) (2020)
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The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences. Nature communications 11 (1) (2020)
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Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer. Nature cancer 1 (2) (2020)
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The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver. Oncogene 39 (32) (2020)
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Landscape of G-quadruplex DNA structural regions in breast cancer. Nature genetics 52 (9) (2020)
Gil Friedman, Oshrat Levi-Galibov, Eyal David, Chamutal Bornstein, Amir Giladi, Maya Dadiani, Avi Mayo, Coral Halperin, Meirav Pevsner-Fischer, Hagar Lavon, Shimrit Mayer, Reinat Nevo, Yaniv Stein, Nora Balint-Lahat, Iris Barshack, H Raza Ali, Carlos Caldas, Einav Nili-Gal-Yam, Omer Karin, Bjørt K Kragesteen, Ruth Scherz-Shouval
Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4 + and PDPN + CAFs to clinical outcome. Nature cancer 1 (7) (2020)
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A network analysis to identify mediators of germline-driven differences in breast cancer prognosis. Nature communications 11 (1) (2020)
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Publisher Correction: Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy. Nature communications 10 (1) (2019)
Jean Hausser, Pablo Szekely, Noam Bar, Anat Zimmer, Hila Sheftel, Carlos Caldas, Omer Karin
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Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy. Nature communications 10 (1) (2019)
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PathTracer: High-sensitivity detection of differential pathway activity in tumours. Scientific reports 9 (1) (2019)
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SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors. Science signaling 11 (515) (2018)