Cryopreserved placental biopsies maintain mitochondrial activity for high-resolution respirometry.

Matteo GiovarelliAnais SeratiSilvia ZecchiniFabiola GuelfiEmilio Clementi Chiara Mandò

Published in: Molecular medicine (Cambridge, Mass.) (2023)

By this protocol, Oxygen Consumption Rate (OCR) measurements of fresh and cryopreserved placental specimens are comparable whereas snap frozen procedure impairs mitochondrial activity.

Keyphrases

high resolution
oxidative stress
randomized controlled trial
umbilical cord
cord blood
minimally invasive
mass spectrometry