Association of Systemic Inflammation with Depressive Symptoms in Individuals with COPD.

Hilary C Strollo Seyed Mehdi NouraieKarin F HothCraig M RileyChad KaroleskiYingze ZhangNicola A HananiaRussell P BowlerJessica BonFrank C Sciurba

Published in: International journal of chronic obstructive pulmonary disease (2021)

Elevated plasma IL-6 levels are associated with depressive symptoms in individuals with COPD independent of airflow limitation and comorbid risk factors for depression. Our results suggest that systemic inflammation may play a significant and possibly bidirectional role in depression associated with COPD.

Keyphrases

depressive symptoms
chronic obstructive pulmonary disease
lung function
social support
sleep quality
cystic fibrosis
air pollution
physical activity