Association between cardiovascular diseases and apical periodontitis: an umbrella review.
Aleksandar JakovljevicHenry Fergus DuncanVenkateshbabu NagendrababuJelena JaćimovićJelena MilasinPaul Michael Howell DummerPublished in: International endodontic journal (2020)
From the limited 'moderate' to 'critically low' quality evidence available, the current umbrella review concluded that a weak association exists between CVDs and AP. In the future, well-designed, longitudinal clinical studies with long-term follow-up are required.