Login / Signup

Systematic review with meta-analysis: high mortality in patients with non-severe alcoholic hepatitis.

Kris BennettDoyo G EnkiMark R ThurszMatthew E CrampAshwin D Dhanda
Published in: Alimentary pharmacology & therapeutics (2019)
Nonsevere alcoholic hepatitis is not benign with 6% and 13% 28-day and 1-year mortality, respectively. This systematic review demonstrates the paucity of high quality studies in patients with nonsevere alcoholic hepatitis. Our analysis suggests that patients who do not meet criteria for severe alcoholic hepatitis are an important and hitherto overlooked clinical group. Full characterisation of clinical outcome and development of treatment strategies to reduce mortality in this group is a priority.
Keyphrases
  • liver injury
  • drug induced
  • systematic review
  • cardiovascular events
  • risk factors
  • early onset
  • randomized controlled trial
  • cardiovascular disease
  • type diabetes
  • coronary artery disease
  • case control