Postnatal induction of muscle fatty acid oxidation in mice differing in propensity to obesity: a role of pyruvate dehydrogenase.

Jana BuresovaPetra JanovskaOndřej KudaJana KrizovaInge Romijnders-van der SteltJaap KeijerHana HansikovaMartin RossmeislJan Kopecky

Published in: International journal of obesity (2005) (2018)

Our results indicate a relatively strong postnatal induction of FA oxidation in skeletal muscle of the obesity-resistant A/J mice. This induction is transient and probably results from suppression of PDH activity, linked with a postnatal surge in plasma leptin levels, independent of AMPK.

Keyphrases

high fat diet induced
skeletal muscle
insulin resistance
preterm infants
metabolic syndrome
fatty acid
weight loss
type diabetes
hydrogen peroxide
weight gain
adipose tissue
body mass index
nitric oxide
blood brain barrier
subarachnoid hemorrhage