Effects of the DL76 Antagonist/Inverse Agonist of Histamine H 3 Receptors on Experimental Periodontitis in Rats: Morphological Studies.

Mariusz GeremekBogna DrozdzowskaDorota Łażewska Katarzyna Kieć-KononowiczJerzy Jochem

Published in: Pharmaceuticals (Basel, Switzerland) (2024)

DL76 is able to inhibit the progression of experimental periodontitis in rats, as demonstrated by a reduction in the inflammatory cell infiltration, a decrease in the RANKL/RANK OPG pathway expression and a reduction in the alveolar bone resorption.

Keyphrases

bone loss
poor prognosis
single cell
oxidative stress
bone mineral density
stem cells
nuclear factor
immune response
binding protein
bone marrow
case control
toll like receptor
inflammatory response
postmenopausal women