Zoledronate in the prevention of Paget's (ZiPP): protocol for a randomised trial of genetic testing and targeted zoledronic acid therapy to prevent SQSTM1-mediated Paget's disease of bone.

Owen CroninLaura ForsythKirsteen GoodmanSteff C LewisCatriona KeerieAllan WalkerMary PorteousRoseanne CetnarskyjLakshminarayan R RanganathPeter L SelbyGeeta HampsonRama ChandraShu HoJon H TobiasSteven Young-MinMalachi J McKennaRachel K CrowleyWilliam D FraserLuigi GennariRanuccio NutiMaria Luisa BrandiJavier Del Pino-MontesJean-Pierre DevogelaerAnne DurnezGiancarlo IsaiaMarco Di StefanoNúria GuañabensJosep BlanchMarkus J SeibelJohn P WalshMark A KotowiczGeoffrey C NicholsonEmma L DuncanGabor MajorAnne HorneNigel L GilchristMaarten BoersGordon D MurrayKeith CharnockDiana WilkinsonR Graham G RussellStuart H Ralston

Published in: BMJ open (2019)

ISRCTN11616770.

Keyphrases

randomized controlled trial
bone mineral density
study protocol
open label
bone loss
stem cells
bone marrow
mesenchymal stem cells