Rotavirus Reassortant-Induced Murine Model of Liver Fibrosis Parallels Human Biliary Atresia.

Sujit K MohantyInna LobeckBryan DonnellyPhylicia DupreeAshley WaltherSarah MoweryAbigail CootsAlexander BondocRachel M SheridanHolly M PolingHaley TempleMonica McNealKarol SestakRuchi BansalGreg Tiao

Published in: Hepatology (Baltimore, Md.) (2020)

This model of rotavirus-induced neonatal fibrosis will provide an opportunity to study disease pathogenesis and has potential to be used in preclinical studies with an objective to identify therapeutic targets that may alter the course of BA.

Keyphrases

liver fibrosis
high glucose
endothelial cells
diabetic rats
oxidative stress
stem cells
risk assessment
mesenchymal stem cells
human health
pluripotent stem cells