Bone health and prevalent fractures in women with polycystic ovary syndrome: a meta-analysis and endocrine-context pathophysiology review.
Jerilynn C PriorSonia ShirinAzita GoshtasebiPublished in: Expert review of endocrinology & metabolism (2023)
Is fracture risk altered by PCOS? Our meta-analysis showed a 25% increased risk of prevalent fracture in PCOS versus controls; this did not reach statistical significance. Future prospective research needs to collect and evaluate ovulation characteristics, progesterone exposure, and adolescent CHC use, in addition to the complex variables that may influence risks for prevalent or incident fragility fractures and/or for cortical and cancellous aBMD values in PCOS.
Keyphrases
- polycystic ovary syndrome
- insulin resistance
- systematic review
- mental health
- healthcare
- public health
- young adults
- human health
- hip fracture
- bone mineral density
- current status
- risk assessment
- randomized controlled trial
- health information
- adipose tissue
- climate change
- postmenopausal women
- metabolic syndrome
- childhood cancer
- social media