Effects of a Single Dose of Ayahuasca in College Students With Harmful Alcohol Use: A Single-blind, Feasibility, Proof-of-Concept Trial.
Lucas Silva RodriguesJosé Augusto Silva ReisGiordano Novak RossiLorena T L GuerraRenan Massanobu MaekawaFlávia de Lima OsórioJosé Carlos BousoFabiana Pereira SantosBeatriz Aparecida Passos Bismara ParanhosMauricio YonamineJaime Eduardo Cecilio HallakRafael Guimarães Dos SantosPublished in: Journal of clinical psychopharmacology (2024)
A significant reduction in days of alcohol consumption was observed 2-3 weeks after ayahuasca intake, but this effect did not survive after Bonferroni correction. The lack of significant effects in alcohol use and other variables may be related to the small sample size and mild/moderate alcohol use at baseline. The present study shows the feasibility of our protocol, paving the way for future larger, controlled studies.