Skeletal muscle-specific DJ-1 ablation-induced atrogenes expression and mitochondrial dysfunction contributing to muscular atrophy.

Shuang ZhangHongmei YanJiyang DingRuwen WangYonghao FengXinyi ZhangXingyu KongHongyu GongXiaodan LuAlice MaYinghui HuaHuan LiuJiani GuoHuanqing GaoZhenqi ZhouRu WangPeijie ChenTiemin LiuXingxing Kong

Published in: Journal of cachexia, sarcopenia and muscle (2023)

Our results illuminate the crucial of skeletal muscle DJ-1 in the regulation of catabolic signals from mechanical stimulation, providing a therapeutic target for muscle wasting diseases.

Keyphrases

skeletal muscle
insulin resistance
poor prognosis
high glucose
diabetic rats
resistance training
drug induced
adipose tissue
endothelial cells
atrial fibrillation