Characterization of a Real-World Response Variable and Comparison with RECIST-Based Response Rates from Clinical Trials in Advanced NSCLC.

Xinran MaLawrence BellomoKelly MageeCaroline S BennetteOlga TymejczykMeghna SamantMelisa TuckerNathan NussbaumBryan E BowserJoshua S KrautAriel Bulua Bourla

Published in: Advances in therapy (2021)

We developed a rwR variable generated from clinician assessments documented in EHRs following radiographic evaluations. This variable provides clinically meaningful information and may provide a real-world measure of treatment effectiveness.

Keyphrases

clinical trial
small cell lung cancer
randomized controlled trial
systematic review
combination therapy
study protocol
smoking cessation