Heparin for diagnostic trans-radial catheterization: Can we have some randomized data?

Marked heterogeneity exists regarding the dose, time and route of administration of unfractionated heparin for diagnostic trans-radial procedures. In an era of smaller caliber hydrophilic radial sheaths, patent hemostasis technique, and shorter compression times, the utility of heparin to prevent radial artery occlusion remains a question. A randomized clinical trial assessing the utility, timing, dose, and route of administration of unfractionated heparin for diagnostic radial catheterization with an aim to prevent radial artery occlusion is needed.