Intranasal ketamine for procedural sedation and analgesia in children: A systematic review.
Naveen PoonaiKyle CantonSamina AliShawn HendrikxAmit ShahMichael MillerGary JoubertMichael RiederLisa HartlingPublished in: PloS one (2017)
IN ketamine administration is well tolerated and without serious adverse effects. Although most participants were deemed adequately sedated with IN ketamine, effectiveness of sedation with respect to superiority over comparators was inconsistent, precluding a recommendation for PSA in children.