BAG3 expression correlates with the grade of dysplasia in squamous intraepithelial lesions of the uterine cervix.

Antonio Raffone Antonio TravaglinoAntonio D'AntonioMargot De MarcoMiriam CacceseMassimo MascoloLuigi InsabatoPio ZeppaAlessandra RosatiAntonio MolloFulvio ZulloMaurizio Guida

Published in: Acta obstetricia et gynecologica Scandinavica (2019)

In CIN/SIL, both distribution and intensity of BAG3 expression correlate directly with the grade of dysplasia, supporting the involvement of BAG3 in all phases of cervical carcinogenesis and its possible diagnostic and prognostic role in cervical premalignant lesions.

Keyphrases

poor prognosis
high grade
binding protein
long non coding rna
high intensity
preterm birth