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Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension.

Eirik OlsenBjörn HolzhauerStevo JuliusSverre E KjeldsenAnne Cecilie K LarstorpGiuseppe ManciaMaria H MehlumRune MoMorten RostrupCamilla L SøraasDion ZappeMichael A Weber
Published in: Blood pressure (2021)
In mostly elderly high-risk hypertensive patients with type 2 diabetes mellitus participating in the VALUE trial, achieving more frequently BP <140/90 mmHg showed a marked protective effect on overall and all cause-specific cardiovascular outcomes. This was not the case for a more frequent achievement of the more intensive BP target, i.e. <130/80 mmHg.
Keyphrases
  • blood pressure
  • hypertensive patients
  • heart rate
  • study protocol
  • phase iii
  • clinical trial
  • middle aged
  • phase ii
  • blood glucose
  • randomized controlled trial
  • type diabetes
  • weight loss