Effectiveness of glutamine for the treatment of radiodermatitis in cancer patients: a meta-analysis of randomized controlled trials.

Hsu-Chieh ChangWen-Yen HuangPo-Huang ChenTsai-Wei HuangMade Satya Nugraha Gautama

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2024)

The meta-analysis indicate that glutamine might lead to a lower incidence of radiodermatitis, and that a glutamine dose of 20-30 g/day might decrease the incidence of moderate to severe dermatitis. Thus, the serious impact of radiodermatitis on treatment follow-up makes the clinical use of glutamine even more important. PROSPERO number: CRD42021254394.

Keyphrases

systematic review
risk factors
randomized controlled trial
early onset
combination therapy
replacement therapy
drug induced