Medulloblastoma of the adult: results from a multicenter retrospective study by AINO (Italian Association of Neuro-Oncology) and SIN (Italian Society of Neurology).
Paola GavianiSimonetti GiorgiaRoberta RudàFederica FranchinoGiuseppe LombardiMarco PossanziniSara SquintuVeronica VillaniMariaausilia TeriacaFrancesco CavallieriMaria CaffoAndrea SalmaggiAndrea BiancoElena AnghileriMariangela FarinottiIrene TramacereAntonio SilvaniPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2020)
The data collected were mainly consistent with the literature. A limitation of this study was the large number of patients lost to follow-up and the lack of molecular data for most patients diagnosed until 2010. An important challenge for the future will be MB biologic characterization in adults, with the identification of specific genetic patterns. It will be important to have more national and international collaborations to provide evidence-based management strategies that attempt to obtain a standard of care.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- palliative care
- healthcare
- systematic review
- prognostic factors
- rheumatoid arthritis
- peritoneal dialysis
- electronic health record
- big data
- patient reported outcomes
- machine learning
- copy number
- genome wide
- dna methylation
- cross sectional
- chronic pain
- single molecule