DNA methylation near CPT1A and changes in triglyceride-rich lipoproteins in response to weight-loss diet interventions.
Xiang LiXiaojian ShaoQiaochu XueMinghao KouCatherine M ChampagneBoryana S KosevaYoriko HeianzaElin GrundbergLydia A BazzanoGeorge A BrayFrank M SacksLu QiPublished in: The Journal of clinical endocrinology and metabolism (2023)
Participants with a higher regional DNAm level at CPT1A benefit more in long-term improvement in triglycerides, particularly in the TRLs and related apolipoproteins when consuming a low-fat weight-loss diet.
Keyphrases
- weight loss
- bariatric surgery
- dna methylation
- roux en y gastric bypass
- gastric bypass
- physical activity
- adipose tissue
- gene expression
- genome wide
- glycemic control
- weight gain
- obese patients
- fatty acid
- type diabetes
- high density
- nk cells
- metabolic syndrome
- body mass index
- skeletal muscle
- insulin resistance
- drug induced