Expression, distribution and function of kinin B1 receptor in the rat diabetic retina.

Soumaya HachanaMenakshi BhatJacques SénécalFrédéric Huppé-GourguesRéjean CoutureElvire Vaucher

Published in: British journal of pharmacology (2018)

Our results support the detrimental role of B1 receptors on endothelial and glial cells in acute and advanced phases of DR. Topical application of the B1 receptor antagonist R-954 seems a feasible therapeutic approach for the treatment of DR.

Keyphrases

induced apoptosis
poor prognosis
editorial comment
liver failure
wound healing
cell cycle arrest
type diabetes
oxidative stress
binding protein
endothelial cells
respiratory failure
drug induced
aortic dissection
long non coding rna
signaling pathway
spinal cord injury
optic nerve
hepatitis b virus
pi k akt