Visible-light-induced synthesis of heteroaryl C -glycosides via decarboxylative C-H glycosylation.
Cuimei ZhangDongqin HeZhaohui MaMi WangYafei ZhuYan LiuJian ChenGuanghui LvYong WuPublished in: Chemical communications (Cambridge, England) (2024)
A photoredox promoted decarboxylative C-H glycosylation has been developed for the synthesis of heteroaryl C -glycosides. This methodology is characterized by its exceedingly simple reaction system, high diastereoselectivity and good functional group tolerance. Moreover, this innovative approach circumvents the need for high temperatures, transition metals, and photocatalysts, providing an environmentally friendly, straightforward, and efficient protocol.