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9-Aryl-3-aminocarbazole as an Environment- and Stimuli-Sensitive Fluorogen and Applications in Lipid Droplet Imaging.

Ryosuke MatsubaraTomoaki KaibaAkito NakataTatsushi YabutaMasahiko HayashiMotonari TsubakiTakashi UchinoEri Chatani
Published in: The Journal of organic chemistry (2019)
Environment-sensitive luminophoric molecules have played an important role in the fields of smart materials, sensing, and bioimaging. In this study, it was demonstrated that depending on the substituents, 9-aryl-3-aminocarbazoles can display aggregation-induced emission and solvatofluorochromism, and the operating mechanism was clarified. The application of these compounds to lipid droplet imaging and fluorescent probes for cysteamine was demonstrated.
Keyphrases
  • high resolution
  • living cells
  • quantum dots
  • single cell
  • high throughput
  • fluorescence imaging
  • fatty acid
  • photodynamic therapy
  • nucleic acid