A classical twin study of PTSD symptoms and resilience: Evidence for a single spectrum of vulnerability to traumatic stress.

Erika J WolfMark W MillerDanielle R SullivanAnanda B AmstadterKaren S MitchellJack GoldbergKathryn M Magruder

Published in: Depression and anxiety (2017)

Genetic factors contribute to a single spectrum of traumatic stress reflecting resilience at one end and high symptom severity at the other. This carries implications for phenotype refinement in the search for molecular genetic markers of trauma-related psychopathology. Rather than focusing only on genetic risk for PTSD, molecular genetics research may benefit from evaluation of the broader spectrum of traumatic stress.

Keyphrases

spinal cord injury
social support
climate change
genome wide
stress induced
posttraumatic stress disorder
depressive symptoms
gene expression
heat stress
physical activity
drug induced
sleep quality
patient reported