Predicting Response to Tocilizumab Monotherapy in Rheumatoid Arthritis: A Real-world Data Analysis Using Machine Learning.

Fredrik D Johansson Jamie E CollinsVincent YauHongshu Guan Seoyoung C Kim Elena LosinaDavid SontagJacklyn StrattonHuong TrinhJeffrey D GreenbergDaniel H Solomon

Published in: The Journal of rheumatology (2021)

The remission prediction scores, derived in RCTs, discriminated patients in RWD about as well as in RCTs. Discrimination was further improved by retraining models on RWD.

Keyphrases

rheumatoid arthritis
data analysis
disease activity
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
randomized controlled trial
ankylosing spondylitis
systemic lupus erythematosus
juvenile idiopathic arthritis
systemic sclerosis
interstitial lung disease
ulcerative colitis