Centrally acting antihypertensives and alpha-blockers in people at risk of falls: therapeutic dilemmas-a clinical review.

Published in: European geriatric medicine (2023)

Centrally acting antihypertensives and alpha-blockers increase the risk of falls through a variety of mechanisms-principally by increasing the risk of hypotension, orthostatic hypotension, arrhythmias and sedation. These agents should be prioritised for de-prescribing in older frailer individuals. We identify a number of tools and a withdrawal protocol to aid the clinician in identifying and de-prescribing these medications.

Keyphrases

community dwelling
primary care
angiotensin converting enzyme
randomized controlled trial
adverse drug
angiotensin ii
physical activity
middle aged
congenital heart disease
emergency department
drug induced