Clinical Characteristics and Outcome of Ceftazidime/Avibactam-Resistant Klebsiella pneumoniae Carbapenemase-Producing Klebsiella pneumoniae Infections: A Retrospective, Observational, 2-Center Clinical Study.
Alessandra OlivaLaura CampogianiGiulia SavelloniPietro VitaleAlessandra LodiFrederica SaccoAlessandra ImeneoLorenzo VolpicelliRiccardo PolaniGiammarco RaponiLoredana SarmatiMario VendittiPublished in: Open forum infectious diseases (2023)
Infections due to CZA-R KPC-Kp often occur in patients who had previously received CZA, especially in the presence of strains susceptible to MEM. Nevertheless, one-third of patients had never received CZA before KPC-Kp CZA-R. Since the major driver for mortality was infection severity, understanding the optimal therapy in patients with KPC-Kp CZA-R infections is of crucial importance.
Keyphrases
- klebsiella pneumoniae
- escherichia coli
- multidrug resistant
- end stage renal disease
- gram negative
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- drug resistant
- acinetobacter baumannii
- type diabetes
- cardiovascular events
- risk factors
- coronary artery disease
- mesenchymal stem cells
- cell therapy
- cross sectional
- pseudomonas aeruginosa
- patient reported outcomes
- replacement therapy