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Clinical Characteristics and Outcome of Ceftazidime/Avibactam-Resistant Klebsiella pneumoniae Carbapenemase-Producing Klebsiella pneumoniae Infections: A Retrospective, Observational, 2-Center Clinical Study.

Alessandra OlivaLaura CampogianiGiulia SavelloniPietro VitaleAlessandra LodiFrederica SaccoAlessandra ImeneoLorenzo VolpicelliRiccardo PolaniGiammarco RaponiLoredana SarmatiMario Venditti
Published in: Open forum infectious diseases (2023)
Infections due to CZA-R KPC-Kp often occur in patients who had previously received CZA, especially in the presence of strains susceptible to MEM. Nevertheless, one-third of patients had never received CZA before KPC-Kp CZA-R. Since the major driver for mortality was infection severity, understanding the optimal therapy in patients with KPC-Kp CZA-R infections is of crucial importance.
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