Stepwise Add-on and Endotype-informed Targeted Combination Therapy to Treat Obstructive Sleep Apnea: A Proof-of-Concept Study.

Atqiya AishahBenjamin K Y TongAmal M OsmanGeoffrey PitcherMichelle DoneganBenjamin C H KwanElizabeth BrownThomas James AltreeRobert AdamsSutapa MukherjeeDanny J Eckert

Published in: Annals of the American Thoracic Society (2023)

These novel prospective findings highlight the potential of precision medicine to inform targeted combination therapy to treat OSA. Clinical trial registered with Australian New Zealand Clinical Trials Registry (ACTRN12618001995268).

Keyphrases

combination therapy
clinical trial
obstructive sleep apnea
positive airway pressure
cancer therapy
phase ii
open label
double blind
study protocol
sleep apnea
phase iii
drug delivery
randomized controlled trial
human health
placebo controlled