A pilot-randomized, double-blind crossover trial to evaluate the pharmacokinetics of orally administered 25-hydroxyvitamin D3 and vitamin D3 in healthy adults with differing BMI and in adults with intestinal malabsorption.

Nipith CharoenngamTyler A KalajianArash ShirvaniGrace H YoonSuveer DesaiAshley McCarthyCaroline M ApovianMichael F Holick

Published in: The American journal of clinical nutrition (2021)

Oral 25(OH)D3 may be a good choice for managing vitamin D deficiency in malabsorption and obesity. This trial was registered at clinicaltrials.gov as (NCT03401541.

Keyphrases

phase iii
double blind
phase ii
study protocol
placebo controlled
clinical trial
open label
weight gain
metabolic syndrome
insulin resistance
body mass index
type diabetes
weight loss
randomized controlled trial
high fat diet induced
decision making
physical activity