A personalised diet approach study: Interaction between PPAR-γ Pro12Ala and dietary insulin indices on metabolic markers in diabetic patients.

Faezeh Abaj Masoumeh Rafiee Fariba Koohdani

Published in: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association (2022)

We revealed that the PPAR-γ Pro12Ala polymorphism was able to intensify the effect of DIL and DII on cardiovascular disease risk factors; risk-allele carriers who consumed a diet with high DIL and DII score were more likely to be obese and have higher inflammatory markers. Also, protective factors against cardiovascular disease risk factors were reduced significantly in this group compared to CC homozygotes.

Keyphrases

risk factors
cardiovascular disease
type diabetes
weight loss
physical activity
insulin resistance
anti inflammatory
metabolic syndrome
glycemic control
fatty acid
cardiovascular risk factors
cardiovascular events
skeletal muscle
coronary artery disease