Biological Synthesis and Process Monitoring of an Aggregation-Induced Emission Luminogen-Based Fluorescent Polymer.

As the most abundant and renewable biopolymer on earth, cellulose can be functionalized for various advanced applications by chemical modification. In addition, fluorescent polymers with aggregation-induced emission (AIE) are generally prepared using chemical approaches, and the biosynthesis of AIE-active polymers are rarely investigated. Herein, fluorescent cellulose was successfully synthesized by bacterial fermentation, where glucosamine-modified AIE luminogen was incorporated into cellulose to achieve AIE-active biopolymers. Excitingly, real-time visualization of the synthetic process was realized, which is crucial for investigating the process of bacterial fermentation. The biosynthesized cellulose exhibited better performance with uniform fluorescence distribution and high stability, compared with that prepared by physical absorption. Additionally, fluorescent mats were fabricated by electrospinning of AIE-active cellulose, demonstrating its great potential applications in flexible display and tissue engineering.