Effectiveness and safety among direct oral anticoagulants in nonvalvular atrial fibrillation: A multi-database cohort study with meta-analysis.
Madeleine DurandMireille E SchnitzerMenglan PangGreg CarneySherif EltonsyKristian B FilionAnat FisherMin JunI Fan KuoAlexis MatteauJ Michael PatersonJacqueline QuailChristel Renouxnull nullPublished in: British journal of clinical pharmacology (2020)
We found that apixaban use is associated with lower risks of stroke and bleeding compared with rivaroxaban, and similar risks compared with dabigatran.
Keyphrases
- atrial fibrillation
- direct oral anticoagulants
- systematic review
- oral anticoagulants
- human health
- catheter ablation
- left atrial
- left atrial appendage
- heart failure
- meta analyses
- venous thromboembolism
- percutaneous coronary intervention
- risk assessment
- randomized controlled trial
- adverse drug
- case control
- coronary artery disease
- emergency department
- pulmonary embolism
- cerebral ischemia