Evaluation of photobiomodulation therapy (117 and 90s) on pain, regeneration, and epigenetic factors (HDAC 2, DNMT3a) expression following spinal cord injury in a rat model.

Ali Motamed NezhadZahra BehrooziKeihan KookliAlireza GhadaksazSeyedalireza Moghaddas FazeliAli MoshiriFatemeh RamezaniMolood Gooniband ShooshtariAtousa Janzadeh

Published in: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology (2023)

PBMT 90 and 117s improved the pain, and functional recovery equally. The regulation of epigenetic mechanisms appears to be a significant effect of PBMT117s, which emphasizes on impact of radiation duration and accumulative energy.

Keyphrases

dna methylation
spinal cord injury
chronic pain
neuropathic pain
pain management
gene expression
stem cells
poor prognosis
spinal cord
wound healing
binding protein
long non coding rna
histone deacetylase
bone marrow