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Early Stepdown From Echinocandin to Fluconazole Treatment in Candidemia: A Post Hoc Analysis of Three Cohort Studies.

E Moreno-GarcíaPedro Puerta-AlcaldeG GariupM Fernández-RuizL E López CortésG CuervoM SalavertP MerinoM MachadoJ GuineaJ García-RodríguezJ Garnacho-MonteroC CardozoJ PemanM MontejoJ FortúnB AlmiranteC CastroJesús Rodríguez-BañoJ M AguadoJ A MartínezJ CarratalàAlex SorianoCarolina García-Vidal
Published in: Open forum infectious diseases (2021)
Early de-escalation is a safe strategy in patients with candidemia caused by fluconazole-susceptible strains with controlled source of bloodstream infection and hemodynamic stability. These results are important to apply antifungal stewardship strategies.
Keyphrases
  • candida albicans
  • escherichia coli
  • open label
  • randomized controlled trial
  • study protocol
  • acute care